Ranjit S. Ranbhor, PhD
Scientific Advisor
Dr. Ranjit S. Ranbhor is a Scientific Advisor with Pergament & Cepeda LLP. Dr. Ranbhor has over 15 years of extensive, diversified pharmaceutical industry experience in pharmaceutical technology, biologics, and Intellectual Property. He is a registered Indian Patent Agent. In India, Dr. Ranbhor prepared and filed numerous patent applications in the areas of pharmaceuticals and biotechnology. For a number of years, Dr. Ranbhor held positions of increasing responsibility with major Indian pharmaceutical companies, including Sun Pharma, Biocon, Aurigene, Cadilla, and Glenmark Pharma, overseeing outside counsel and managing collaboration with major brand and generic companies. Dr. Ranbhor's prior work experience in India included in-licensing/out-licensing (due diligence) IP support, patent dispute settlement, freedom-to-operate analysis, patent enforcement, competitive landscape analysis. Dr. Ranbhor has been a reviewer of distinctive, internationally recognized scientific journals and books in the field of pharmaceutical biotechnology.
Specialty Areas: In-depth scientific expertise in the area of pharmaceutical biotechnology with business knowledge; Technology evaluation and company profiling; In-licensing, out-licensing. Biosimilars, Novel Biologics. Patent Portfolio Management, Freedom to operate analysis, Scope of protection analysis.
Education: Post-Doctoral Research Fellow, Georgetown University (2007)
Ph.D. Biotechnology, IIT Bombay (2006)
MS. Pharmaceutical Biotechnology, NIPER (2000)
Bachelor in Pharmaceutical Sciences, Pune University (1998)
Post-Graduate Diploma in Patent Laws, NALSAR (2011)
Post-Graduate Diploma in Business Administration, SMU (2010)
Certificate Course – Pharma Regulatory Affairs (2010)
Affiliations: Patent Agent - India
Society for Biological Chemists (Life Member)
Indian Peptide Society (Life Member)
Patents/Applications (as co-inventor):: 1: IN201721010840: Method for making KEX1 protease sensitive polypeptides using yeast strain
2: PCT/IB2018/051788: Method for making KEX1 protease sensitive polypeptides using yeast strain
Publications:
Biosimilars:
- Singh SK, Pokalwar S, Bose S, Gupta S, Almal S, Ranbhor RS. Structural and functional comparability study of anti-CD20 monoclonal antibody with reference product. Biologics. 2018 Nov 23;12:159-170.
- Singh SK, Nage N, Jagani H, Maiti M, Ranbhor RS. Glycan mapping of recombinant human follicle stimulating hormone by mass spectrometry. Reprod Biol. 2018 Dec;18(4):380-384.
- Thennati R, Singh SK, Nage N, Patel Y, Bose SK, Burade V, Ranbhor RS. Analytical characterization of recombinant hCG and comparative studies with reference product. Biologics. 2018 Jan 30;12:23-35.
NCE/Small molecules:
- Khatri M, Rai SK, Ranbhor R, Kishore K, Tiwari M. Synthesis and pharmacological evaluation of [(4-arylpiperazin-1-yl)-alkyl]-carbamic acid ethyl ester derivatives as potential anxiolytic agents. Arch Pharm Res. 2012 Jul;35(7):1143-52.
IP/ Patents:
- Sarkar M, Ranbhor R. Book Chapter 9 titled “Patents in peptide science” Elsevier publication, in Book titled “De novo Peptide Design” 2022 (In press)
Protein Engineering/Design:
- Prakash V, Ranbhor R, Ramakrishnan V. De Novo Designed Heterochiral Blue Fluorescent Protein. ACS Omega. 2020 Oct 6;5(41):26382-26388.
- Ranbhor R, Kumar A, Patel K, Ramakrishnan V, Durani S. Automated design evolution of stereochemically randomized protein foldamers. Phys Biol. 2018 Mar 1;15(3):036001.
- Ramakrishnan V, Ranbhor R, Durani S. Simulated folding in polypeptides of diversified molecular tacticity: implications for protein folding and de novo design. Biopolymers. 2005 Jun 5;78(2):96-105.
Bioinformatics:
- Ranbhor R, Kumar A, Tendulkar A, Patel K, Ramakrishnan V, Durani S. IDeAS: automated design tool for hetero-chiral protein folds. Phys Biol. 2018 Aug 14;15(6):066005.
- Kumar A, Ranbhor R, Patel K, Ramakrishnan V, Durani S. Automated protein design: Landmarks and operational principles. Prog Biophys Mol Biol. 2017 May; 125:24-35.
Bioinformatics:
- Kumar A, Ramakrishnan V, Ranbhor R, Patel K, Durani S. Homochiral stereochemistry: the missing link of structure to energetics in protein folding. J Phys Chem B. 2009 Dec 24;113(51):16435-42.
- Ranbhor R, Ramakrishnan V, Kumar A, Durani S. The interplay of sequence and stereochemistry in defining conformation in proteins and polypeptides. Biopolymers. 2006 Dec 5;83(5):537-45.
- Ramakrishnan V, Ranbhor R, Kumar A, Durani S. The link between sequence and conformation in protein structures appears to be stereochemically established. J Phys Chem B. 2006 May 11;110(18):9314-23.
- Ramakrishnan V, Ranbhor R, Durani S. Existence of specific "folds" in polyproline II ensembles of an "unfolded"alanine peptide detected by molecular dynamics. J Am Chem Soc. 2004 Dec 22;126(50):16332-3.
Languages:English, Hindi, Marathi